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The drug attenuates arterial inflammation and neointimal formation after injury in low-density lipoprotein receptor-deficient mice [109] andbesides the expected decrease in glucose and hemoglobin A1cleads also to a decrease in serum lipids in humans [110]

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In 2014, Nova Nordisks GLP-1 drug Saxenda was approved by the FDA as a treatment for obesity, and since then, others have followed

Oral semaglutide has very specific administration instructions to ensure proper absorption: it should be taken with no more than 4 ounces of plain water at least 30 minutes before the first food, beverage, or other oral medications of the day